Thermo Fisher Scientific MSI2 Polyclonal Antibody
MSI2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC, IP 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫드에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–217 of Human Musashi 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548498 |
Product Specific Information
- Recommended positive controls: IMR32, MCF-7, mouse brain
- Predicted reactivity: Mouse (100%), Xenopus laevis (97%), Bovine (84%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Msi2 (Musashi homolog 2), also known as MSI2H, is a 328 amino acid protein localized in the cytoplasm with two RNA recognition motif (RRM) domains. It acts as an RNA-binding protein involved in regulating mRNA expression, contributing to stem cell proliferation and maintenance in the central nervous system. Msi2 is phosphorylated posttranslationally and upregulated following brain injury, suggesting a role in tissue regeneration. Chromosomal aberrations involving Msi2 are linked to chronic myeloid leukemia progression. Expression is ubiquitous but at low levels.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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