Thermo Fisher Scientific Periostin Monoclonal Antibody (OTI2D10), TrueMAB
Periostin 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화되어 있습니다. 인체 유래 항원(aa 538-781)을 면역원으로 제작되었으며, 액상 형태로 제공됩니다. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적으로 유지됩니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 538–781 of human POSTN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally identified as an osteoblast-specific factor. It is a secreted protein that binds heparin and serves as a ligand for αVβ3 and αVβ5 integrins. In preosteoblasts, Periostin functions as a cell adhesion molecule involved in osteoblast recruitment, spreading, and attachment. It is primarily expressed in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, but is upregulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression is increased by BMP2 and TGF-β1. The protein contains a signal sequence, a cysteine-rich domain, four fasciclin-like repeats, and a C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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