Thermo Fisher Scientific Phospho-STAT2 (Ser734) Polyclonal Antibody
Phospho-STAT2 (Ser734) 항체로 인간 및 비인간 영장류 STAT2 단백질의 인산화 형태를 검출. Western blot 및 ELISA에 적합하며, 친화 크로마토그래피로 정제된 고순도 항체. 안정한 액상 형태로 -20°C에서 보관.
- 카탈로그번호
- 600-401-H38x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-STAT2 (Ser734) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | STAT2 pS734 antibody was prepared from whole rabbit serum produced by repeated immunizations with a phosphorylated synthetic peptide corresponding to serine 734 near the C-terminus of human STAT2 protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
STAT2 pS734 affinity purified antibody is directed against human STAT2 protein and is specific for phosphorylated S734 of human STAT2.
BLAST analysis suggests cross-reactivity with STAT2 pS734 protein from human and monkey sources based on homology with the immunizing sequence. Reactivity against homologs from other species is not known.
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, forming homo- or heterodimers that translocate to the nucleus to act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and ISGF3G, acting as a transactivator but lacking direct DNA-binding ability. STAT2 also interacts with transcription adaptor proteins P300/CBP (EP300/CREBBP), which are involved in blocking IFN-alpha responses by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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