Thermo Fisher Scientific LMBR1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LMBR1. Recombinant protein control fragment (Product #RP-91225). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LMBR1,uniProtId:Q8WVP7-1,ncbiNodeId:9606,antigenRange:217-291,antigenLength:490,antigenImageFileName:PA5-53452_LMBR1_Q8WVP7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53452_LMBR1_Q8WVP7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643400

Product Specific Information

Immunogen sequence: FTVMGQLLVK PTILEDLDEQ IYIITLEEEA LQRRLNGLSS SVEYNIMELE QELENVKTLK TKLERRKKAS AWERN

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.