
Thermo Fisher Scientific Cannabinoid Receptor 2 (extracellular) Polyclonal Antibody
인간 CB2 수용체의 세포외 영역을 표적으로 하는 Rabbit Polyclonal Antibody로, WB, ICC/IF, Flow Cytometry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공되어 안정적인 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)NGSKDGLDSNPMKD, corresponding to amino acid residues 11–24 of human CB2 receptor, extracellular N-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW) depending on sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Cannabinoids exert their physiological effects through two G protein-coupled receptors, CB1 and CB2. Both receptors inhibit adenylyl cyclase and stimulate MAPK signaling.
CB1 receptors modulate ion channels through G-protein interactions and mediate psychoactive effects by inhibiting presynaptic N- and P/Q-type calcium channels.
CB2 receptors primarily function in the immune system but may also be present in the central nervous system, including the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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