Thermo Fisher Scientific CDKL2 Polyclonal Antibody
CDKL2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 비결합형 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Thermo Fisher Scientific CDKL2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: - [References Not Provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human CDKL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555348 |
Target Information
The activation of signal transduction pathways by growth factors, hormones, and neurotransmitters is mediated by the MAP kinases ERK1 and ERK2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif.
The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain, and lung.
KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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