Thermo Fisher Scientific Phospho-PDGF Receptor beta (Tyr740) Polyclonal Antibody
PDGFRB (Tyr740) 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-PDGF Receptor beta (Tyr740) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human PDGF Receptor beta around the phosphorylation site of Tyr740 [GG(p-Y)MD] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PDGFRB (platelet-derived growth factor receptor beta) is a receptor tyrosine kinase implicated in atherogenesis and cellular transformation by the SIS oncogene. These growth factors act as mitogens for cells of mesenchymal origin. The receptor may form homodimers or heterodimers with PDGF receptor alpha, depending on the growth factor bound. The PDGFRB gene is located on chromosome 5, near genes for GM-CSF and M-CSF receptor, and may be involved in the 5-q syndrome. A translocation between chromosomes 5 and 12 that fuses PDGFRB (CD140b) with the ETV6 leukemia gene results in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.