Thermo Fisher Scientific RAD54L2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000
• Publications: -

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.

Target Information

RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325, or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family. It contains a helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 functions as a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner and is post-translationally modified (sumoylation or phosphorylation) upon DNA damage.

Adrenergic receptors (ARs) include four general types (α1, α2, β1, and β2) found in different tissues, differing in their affinities and responses to various agonists and antagonists. ARs are coupled to specific intracellular effectors through heterotrimeric G proteins and play a critical role in prostate cancer development. Transcriptional activity of AR is partly regulated by coregulatory proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.