Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI17A6), TrueMAB
인간 NPPB 단백질(아미노산 27-102)을 항원으로 한 마우스 단일클론 항체. Western Blot과 Luminex 분석에 적합. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 용이. 심혈관 관련 연구용으로 최적화된 TrueMAB 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI17A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene belongs to the natriuretic peptide family and encodes a secreted cardiac hormone. It undergoes two cleavage events—one intracellular and one extracellular. The protein promotes natriuresis, diuresis, vasorelaxation, and inhibits renin and aldosterone secretion, playing a key role in cardiovascular homeostasis. Elevated levels in blood are indicative of heart failure. Mutations are linked to postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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