Thermo Fisher Scientific B7-H3 Monoclonal Antibody (008)
Human B7-H3/CD276 특이성을 가진 Mouse monoclonal antibody. ELISA에 적합하며, 단백질 A로 정제된 1 mg/mL 액상 형태. 보존제 무첨가로 고순도이며, 단기 4°C, 장기 -20°C 보관 권장.
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- MA530252
- 판매단위
- pk
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Applications
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 008 |
| Immunogen | Recombinant Human B7-H3/CD276 Protein (Met1–Thr461) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786007 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human B7-H3/CD276.
Target Information
CD276 (B7-H3) is a member of the B7 family of co-stimulatory molecules. It is a type I transmembrane protein that induces proliferation of CD4⁺ and CD8⁺ T cells, enhances cytotoxic T cell generation, and selectively stimulates interferon gamma production.
Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and it is also widely expressed in peripheral tissues such as heart, kidney, testis, and colon.
In humans, CD276 exists as two isoforms resulting from gene duplication and differential splicing.
CD276 is reported to have therapeutic potential for regulating cell-mediated immune responses to cancer, particularly in combination with anti-angiogenic therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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