Thermo Fisher Scientific B7-H3 Monoclonal Antibody (01)
Human B7-H3/CD276 인식 마우스 모노클로날 항체로, ELISA에 적합합니다. 보존제가 없는 액상 형태이며 Protein A로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:250–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 01 |
| Immunogen | Recombinant Human B7-H3/CD276 Protein (Met1–Thr461) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786008 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human B7-H3/CD276.
Target Information
CD276, also known as B7-H3, is a member of the B7 family of co-stimulatory molecules.
It is a type I transmembrane protein that induces proliferation of CD4⁺ and CD8⁺ T cells, enhances cytotoxic T cell generation, and selectively stimulates interferon gamma production.
Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines and is widely expressed in peripheral tissues such as heart, kidney, testis, and colon.
In humans, CD276 exists as two isoforms resulting from gene duplication and differential splicing.
CD276 has therapeutic potential for regulating cell-mediated immune responses in cancer, particularly when combined with anti-angiogenic therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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