Thermo Fisher Scientific IL12RB2 Polyclonal Antibody
IL12RB2 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. IHC(P)에서 1:50~1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관하며, -20°C에서 안정적으로 저장됩니다.
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- PA550685
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human interleukin 12 receptor, beta 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2636137 |
Product Specific Information
The antibody detects endogenous levels of total IL12RB2 protein.
Target Information
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. Coexpression of this and IL12RB1 proteins leads to the formation of high-affinity IL12 binding sites and reconstitution of IL12-dependent signaling. Expression of this gene is up-regulated by interferon gamma in Th1 cells and plays a role in Th1 cell differentiation. Up-regulation of this gene is associated with several infectious diseases, such as Crohn’s disease and leprosy, contributing to the inflammatory response and host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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