Thermo Fisher Scientific ITPR3 Polyclonal Antibody
Human ITPR3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관. 내인성 ITPR3 단백질 검출에 적합한 연구용 항체.
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Thermo Fisher Scientific ITPR3 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to internal residues of human inositol 1,4,5-trisphosphate receptor, type 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636140 |
Product Specific Information
The antibody detects endogenous levels of total ITPR3 protein.
Target Information
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
The receptor contains a calcium channel at the C-terminus and a ligand-binding site at the N-terminus.
Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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