Thermo Fisher Scientific CD272 (BTLA) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 2.5 µg/mL

Product Specifications

Product Specific Information

• Positive controls that may be used include:
  • Jurkat Cell Lysate
  • Human Small Intestine Tissue Slide

Target Information

BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor, regulating immune responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation. It remains expressed on Th1 cells, but not Th2 cells. BTLA interacts with the TNF receptor family member HVEM, playing a key role in lymphocyte activation and homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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