Thermo Fisher Scientific Mist1 Polyclonal Antibody
Thermo Fisher Scientific의 Mist1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 WB 및 IHC(P)에 사용됩니다. Rabbit IgG 기반의 비결합 항체로, 항원 친화 크로마토그래피로 정제되었습니다. 세포 분화 조절 및 근육 관련 유전자 발현 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | BHLHA15 antibody was raised against an 18 amino acid peptide near the center of human BHLHA15. The immunogen is located within amino acids 60–110 of BHLHA15. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890471 |
Product Specific Information
Positive controls that may be used include:
- Rat Small Intestine Tissue Lysate
- Human Small Intestine Tissue Slide
Target Information
Mist1 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. It may also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Mist1 serves as a key regulator of acinar cell function, stability, and identity. It is required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. Mist1 may function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. It binds to the E-box consensus sequence 5'-CANNTG-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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