
Thermo Fisher Scientific Complexin-3/4 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:300-1:2,000
Immunohistochemistry (IHC)
1:300-1:2,000
Miscellaneous PubMed (Misc)
-
View 2 publications 2 publications
Product Specifications
Species Reactivity
Human, Mouse
Published species
Not Applicable
Host/Isotype
Rabbit / Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from n-terminal region of human Complexin-3 conjugated to an immunogenic carrier protein was used as the antigen if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CPLX3/CPLX4,uniProtId:Q8WVH0-1,ncbiNodeId:9606,antigenRange:1,antigenLength:158,antigenImageFileName:OSC00179W-100UL_CPLX3CPLX4_Q8WVH0-1_Rabbit.svg,antigenImageFileNamePDP:OSC00179W-100UL_CPLX3CPLX4_Q8WVH0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide shares 90% identity with Complexin-4.
Specificity of this antibody: Complexin-3 and 4.
Target Information
The function of this target is Complexin-3 & 4: Positively regulates a late step in synaptic vesicle exocytosis. Tissue Specificity: Complexin-3: Present in many brain regions, including hippocampus and cerebellum. In the retina, present both at conventional amacrine cell synapses and at photoreceptor ribbon synapses (at protein level). Complexin-4: Present specifically in the retina, at rod photoreceptor ribbon synapses. Not expressed at conventional amacrine cell synapses, nor at cone photoreceptor ribbon synapses (at protein level). Subcellular Location: Complexin-3 & 4: Membrane; Lipid-anchor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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