Thermo Fisher Scientific ZNF638 Polyclonal Antibody
Human ZNF638 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA557815
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZNF638 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZNF638. Recombinant protein control fragment (Product #RP-95983). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2650252 |
Product Specific Information
Immunogen sequence:
GLLKPTSARS GLAESSSKFK PTQSSLTRGG SGRISALQGK LSKLDYRDIT KQSQETEARP SIMKRDDSNN KTLAEQNTKN PK
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 76%
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions related to transcriptional activation or repression.
NP220 (Nuclear protein 220), also known as Zinc finger protein 638 (ZNF638) or Cutaneous T-cell lymphoma-associated antigen se33-1, is a 1978 amino acid protein containing one matrin-type zinc finger and two RRM (RNA recognition motif) domains, suggesting a role in transcriptional regulation.
NP220 binds to double-stranded DNA fragments by recognizing clusters of cytidines, interacts with FHL-2, and may be phosphorylated by ATM or ATR upon DNA damage.
It exists as five isoforms due to alternative splicing events. Isoform five of NP220 is a tumor-associated antigen found in several cutaneous T-cell lymphoma (CTCL) cases, including mycosis fungoides and Sezary syndrome patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.