Thermo Fisher Scientific HAT1 Polyclonal Antibody
Human, Mouse, Rat 반응성의 HAT1 폴리클로날 항체로 Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며 PBS 및 글리세롤 버퍼에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HAT1. Recombinant protein control fragment (Product #RP-96077). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642314 |
Product Specific Information
Immunogen sequence:
KFKINKQHAR RVYEILRLLV TDMSDAEQYR SYRLDIKRRL ISPYKKKQRD LAKMRKCLRP EELTNQMNQI EISMQHEQLE ESFQELVEDY RRVIERLA
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
The protein encoded by this gene is a type B histone acetyltransferase (HAT) involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are then imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. This HAT acetylates soluble histone H4 at lysines 5 and 12, and to a lesser degree histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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