Thermo Fisher Scientific TNFAIP6 Polyclonal Antibody
TNFAIP6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체입니다. Western blot 및 IHC에 적합하며, 인간·마우스·랫트 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되어 높은 순도(>95%)를 제공합니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TNFAIP6 Polyclonal Antibody
Thermo Fisher Scientific TNFAIP6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human TNFAIP6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719736 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The TSG6 gene is transcribed in normal fibroblasts and activated by cytokines TNF-α and IL-1 at AP-1 and NF-IL6 promoter sites.
TSG-6 is a glycoprotein and a member of the hyaluronan-binding protein family, including cartilage link protein, proteoglycan core protein, and CD44.
It is highly homologous to CD44, particularly in the hyaluronic acid-binding domain.
TSG-6 expression is rapidly induced by TNF-α, IL-1, and lipopolysaccharide in normal fibroblasts, peripheral blood mononuclear cells, synovial cells, and chondrocytes.
Presence in synovial fluid suggests a role in rheumatoid arthritis.
TSG-6 forms a stable complex with inter-alpha-inhibitor (IαI) components and enhances its inhibitory effect on plasmin protease activity.
Together, TSG-6 and IαI modulate the protease network and help inhibit inflammation.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.