Thermo Fisher Scientific NDE1 Recombinant Rabbit Monoclonal Antibody (22H20L67)
NDE1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 적합합니다. 높은 특이성과 일관된 로트 간 재현성을 제공합니다. 인간, 마우스, 랫트 반응성이 있으며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 22H20L67 |
| Immunogen | Protein corresponding to human NDE1 (aa1–aa346) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2692257 |
Product Specific Information
This antibody is predicted to react with Monkey, Cat, and Horse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
NDE1 is a member of the nuclear distribution E (NudE) family of proteins. It localizes at the centrosome and interacts with other centrosomal components as part of a multiprotein complex that regulates dynein function. NDE1 plays an essential role in microtubule organization, mitosis, and neuronal migration. Mutations in the NDE1 gene are associated with Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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