Thermo Fisher Scientific PAM Polyclonal Antibody
Thermo Fisher Scientific의 PAM 폴리클로날 항체는 Western blot, IHC(P), ICC/IF에 적합합니다. Human PAM 단백질을 면역원으로 사용하였으며, 항원 친화 크로마토그래피로 정제되었습니다. 0.1 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PAM. Recombinant protein control fragment (Product # RP-88689) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645191 |
Product Specific Information
Immunogen sequence:
HLGKVVSGYR VRNGQWTLIG RQSPQLPQAF YPVGHPVDVS FGDLLAARCV FTGEGRTEAT HIGGTSSDEM CNLYIMYYME AKHAVSFMTC TQNVAPDMFR TIPPEANIPI PVKSDMVMMH EHHKETEYKD KIPLLQQPKR EEEEVL
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 88%
Target Information
SNX33 (sorting nexin-33), also known as SH3PX3, SH3PXD3C, or SNX30, is a 574 amino acid protein that interacts with ADAM15 and FAS-L.
Belonging to the sorting nexin family, SNX33 contains one BAR domain, one PX (phox homology) domain, and one SH3 domain.
The gene encoding SNX33 spans over 14,000 bases and maps to human chromosome 15q24.2.
Chromosome 15 comprises approximately 106 million base pairs and encodes more than 700 genes, representing about 3% of the human genome.
Angelman and Prader-Willi syndromes are associated with loss or deletion of genes in the 15q11–q13 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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