Thermo Fisher Scientific DTX4 Polyclonal Antibody
Rabbit polyclonal antibody against human DTX4 for Western blot applications. Recognizes C-terminal peptide (aa 570–619) of DTX4. High sequence homology across species. Supplied unconjugated in PBS buffer with sucrose and sodium azide. For research use ...
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Thermo Fisher Scientific DTX4 Polyclonal Antibody
Applications
- Western Blot (WB): Tested at 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human DTX4 (aa 570–619) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576419 |
Product Specific Information
- Peptide sequence: TVIWNEVHHK TEFGSNLTGH GYPDANYLDN VLAELAAQGI SEDSTAQEKD
- Sequence homology:
- Cow: 93%
- Dog: 100%
- Guinea Pig: 100%
- Horse: 100%
- Human: 100%
- Mouse: 86%
- Rabbit: 86%
- Rat: 93%
Target Information
DTX4 is a regulator of Notch signaling, a pathway involved in cell-cell communication and cell-fate determination. It acts as an ubiquitin ligase protein in vivo, mediating Lys48-linked polyubiquitination and promoting degradation of TBK1. Targeting to TBK1 requires interaction with NLRP4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-46146_DTX4_Q9Y2E6-1_Rabbit_PDP.jpeg
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