Thermo Fisher Scientific DENND1C Polyclonal Antibody
Rabbit polyclonal antibody against human DENND1C protein. Validated for Western blot at 1 µg/mL. Recognizes C-terminal region (aa 741-790). Supplied as liquid, 0.5 mg/mL, affinity purified, stored at -20°C. For research use only.
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Applications
- Western Blot (WB): Tested at 1 µg/mL
- Publications: Not specified
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human DENND1C (aa 741–790) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606859 |
Product Specific Information
- Peptide sequence: PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP
- Sequence homology: Human: 100%
Target Information
Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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