Thermo Fisher Scientific NK1, Tachykinin Receptor 1 Receptor Polyclonal Antibody
Human NK1 (Tachykinin Receptor 1) 인식 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 신경계 및 염증 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide with sequence SSRSDSKTMTESFSFSSNVLS corresponding to amino acids 387–407 of human NK1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Tachykinin Receptor 1 (NK1) is a member of the Tachykinin Receptor subfamily involved in phosphatidylinositol metabolism mediated by the tachykinin substance P (neurokinin 1).
It plays a role in depression, anxiety, and stress regulation, as well as in behavioral responses, neuronal survival, and cardiovascular and respiratory functions.
NK1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two splice variants are known.
Expression is primarily in the brain, and also in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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