Thermo Fisher Scientific NK1, Tachykinin Receptor 1 Polyclonal Antibody
Thermo Fisher Scientific의 NK1 (Tachykinin Receptor 1) 폴리클로날 항체로, 인간 시료에서의 WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체이며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide with sequence SSRSDSKTMTESFSFSSNVLS corresponding to amino acids 387–407 of human NK1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Tachykinin Receptor 1 (also known as Neurokinin 1 receptor) is a member of the Tachykinin Receptor subfamily. It mediates phosphatidylinositol metabolism via the tachykinin substance P and is associated with depression, anxiety, and stress regulation. This receptor plays roles in behavioral responses, neuronal survival, and cardiovascular and respiratory functions. It has also been implicated in rheumatoid arthritis and osteoarthritis. Two variants are produced by alternative splicing. Expression is primarily observed in the brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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