Thermo Fisher Scientific HSP27 Monoclonal Antibody (C1)
HSP27 단백질을 표적하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone C1). Western blot, IHC, ICC/IF에 적합하며, 인간 및 돼지 반응성. 액상 형태, Protein A/G 정제, 안정적인 PBS/glycerol buffer 구성. 연구용으로 사용.
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Thermo Fisher Scientific HSP27 Monoclonal Antibody (C1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–30 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1 |
| Immunogen | Recombinant Human Hsp27 protein (Thr2–Lys205, Accession #P04792) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093471 |
Target Information
In response to environmental stress, many cells increase expression of heat shock or stress proteins. HSPB1 (Heat Shock Protein Beta-1, also known as HSP27) acts as a molecular chaperone maintaining denatured proteins in a folding-competent state. It contributes to stress resistance and actin organization, and regulates biological processes such as phosphorylation and axonal transport of neurofilament proteins. Mutations in HSPB1 can lead to Charcot-Marie-Tooth disease type 2F and distal hereditary motor neuronopathy type 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-50979_HSP27_P04792-1_House_mouse.svg, MA5-50979_HSP27_P04792-1_House_mouse_PDP.jpeg)
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