
Thermo Fisher Scientific HSP27 Monoclonal Antibody (C1)
HSP27 단백질을 표적하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone C1). Western blot, IHC, ICC/IF에 적합하며, 인간 및 돼지 반응성. 액상 형태, Protein A/G 정제, 안정적인 PBS/glycerol buffer 구성. 연구용으로 사용.
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Thermo Fisher Scientific HSP27 Monoclonal Antibody (C1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–30 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1 |
| Immunogen | Recombinant Human Hsp27 protein (Thr2–Lys205, Accession #P04792) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093471 |
Target Information
In response to environmental stress, many cells increase expression of heat shock or stress proteins. HSPB1 (Heat Shock Protein Beta-1, also known as HSP27) acts as a molecular chaperone maintaining denatured proteins in a folding-competent state. It contributes to stress resistance and actin organization, and regulates biological processes such as phosphorylation and axonal transport of neurofilament proteins. Mutations in HSPB1 can lead to Charcot-Marie-Tooth disease type 2F and distal hereditary motor neuronopathy type 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-50979_HSP27_P04792-1_House_mouse.svg, MA5-50979_HSP27_P04792-1_House_mouse_PDP.jpeg)
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