Thermo Fisher Scientific AKR1C1 Monoclonal Antibody (5-F10)
AKR1C1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 및 생쥐 반응성, Protein A 정제, 고농도(2 mg/mL) 액상 형태로 제공되며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5-F10 |
| Immunogen | Recombinant protein within Human AKR1C1 aa 180–323 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS (pH 7.4) with 50% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802489 |
Target Information
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. The gene shares high sequence identity with three other family members and is clustered with those genes at chromosome 10p15–p14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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