Thermo Fisher Scientific LARG Polyclonal Antibody
Human ARHGEF12 단백질(1494–1544 aa)을 면역원으로 한 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제. 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1494 and 1544 of human leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12, UniProt ID: Q9NZN5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli acting through G protein–coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signaling. It has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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