
Thermo Fisher Scientific alpha Internexin Recombinant Rabbit Monoclonal Antibody (ARC2054)
alpha Internexin 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC, ELISA에 적합. 인간, 마우스, 랫트 반응성. HEK293 세포에서 발현된 IgG 형 항체로, 신경세포 발달 연구에 유용. -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2054 |
| Immunogen | Synthetic peptide corresponding to amino acids 350–450 of human Alpha Internexin (Q16352) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.13 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3) with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898000 |
Product Specific Information
- Positive Samples: U-87MG, Mouse brain, Rat brain
- Immunogen sequence:
EVAGYQDSIG QLENDLRNTK SEMARHLREY QDLLNVKMAL DIEIAAYRKL LEGEETRFST SGLSISGLNP LPNPSYLLPP RILSATTSKV SSTGLSLKKE E
Target Information
alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the neurofilament triplet proteins NF-L, NF-M, and NF-H, having similar protein sequence motifs and intron organization. Many mature neurons contain alpha-internexin along with NF-L, NF-M, and NF-H, while in some neurons it is the only neurofilament subunit expressed.
Antibodies to alpha-internexin serve as unique probes for studying neuronal types and tracing their processes in tissue sections and culture. Its early developmental expression makes it a useful marker for neuronal progenitor cells and cells committed to the neuronal lineage. Potential applications in brain tumor studies remain to be explored.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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