Thermo Fisher Scientific ATP1A3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitute antibody with 50 µL of double distilled water (DDW).
• Store reconstituted solution at 4°C for up to 1 week.
• For longer storage, aliquot and keep at -20°C.
• Avoid multiple freeze-thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).
• Peptide sequence: (C)DKKDDKSSPKKSK
• Homology: Mouse – identical residues; Human – 11/13 amino acids identical.

Target Information

The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for ATP-dependent transport of sodium and potassium across the cell membrane.
This enzyme is related to other ATPases such as SERCA and PMCA. It consists of a large transmembrane catalytic alpha subunit and a smaller glycoprotein beta subunit.
There are three isoforms of the alpha subunit (α1, α2, α3) and two of the beta subunit (β1, β2), each showing tissue-specific expression.
The alpha-3 subunit is mainly found in neuronal, skeletal, cardiac muscle, lung, and stomach tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.