Thermo Fisher Scientific Phospho-MLK3 (Ser674) Polyclonal Antibody
MLK3 단백질의 Ser674 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB 및 ELISA에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. MAPK 및 JNK 신호전달 연구용으로 사용됩니다.
- 카탈로그번호
- PA540303
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- View 1 publication
ELISA
- Tested Dilution: 1:5,000
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human MLK3 around the phosphorylation site of S674 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607025 |
Product Specific Information
This antibody is predicted to react with human and rat based on sequence homology.
Target Information
MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. It contains a SH3 domain and a leucine zipper-basic motif, preferentially activating MAPK8/JNK kinase and functioning as a positive regulator of JNK signaling. MLK3 can directly phosphorylate and activate IκB kinase α and β, and is involved in NF-κB transcriptional activity mediated by Rho family GTPases and CDC42.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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