Thermo Fisher Scientific Phospho-EpoR (Tyr426) Polyclonal Antibody
인간, 마우스, 랫트에서 반응하는 Phospho-EpoR (Tyr426) 폴리클로날 항체로, 웨스턴 블롯에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 기반 용액 형태로 제공됩니다. 에리트로포이에틴 수용체 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human EpoR around the phosphorylation site of Y426 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609270 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
EpoR encodes the erythropoietin receptor, a member of the cytokine receptor family. Binding of erythropoietin activates Jak2 tyrosine kinase, which triggers intracellular pathways such as Ras/MAP kinase, PI3K, and STAT transcription factors. Activated EpoR supports erythroid cell survival. Mutations in this gene are linked to erythroleukemia and familial erythrocytosis, and dysregulation may influence tumor growth. Multiple transcript variants arise from alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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