Thermo Fisher Scientific PolE3/p17 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
• Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan

Target Information

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes: sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. MtCK occurs in dimeric and octameric forms, unlike cytosolic creatine kinase isoenzymes, which are exclusively dimeric. Sarcomeric mitochondrial creatine kinase shares 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs shared among nuclear genes encoding mitochondrial proteins, potentially essential for coordinated activation during mitochondrial biogenesis. Three transcript variants encoding the same protein have been identified.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.