
Thermo Fisher Scientific NR5A1 Monoclonal Antibody (OTI1D2), TrueMAB
Human NR5A1 단백질(아미노산 1-262)에 특이적인 Mouse IgG2a 단일클론 항체. Western blot에서 1:2,000 희석으로 검증됨. 무보존제, 동결건조 형태로 제공되며 연구용에 적합. SF-1 관련 내분비계 발달 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–262 of human NR5A1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system.
It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2), which are necessary for interaction with nuclear receptors, coactivators, and corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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