Thermo Fisher Scientific GPR18 Polyclonal Antibody
다중 응용(IHC, ICC, Flow, ELISA)에 적합한 GPR18 폴리클로날 항체. 인간 GPR18 유래 합성 펩타이드 면역원으로 제작. 비결합형 액상 형태로 제공되며, -20°C에서 보관. 면역계 및 신경전달 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human G protein coupled receptor 18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
The G-protein-coupled receptor (GPCR) superfamily consists of approximately 600–1,000 members, making it the largest known class of molecular targets with proven therapeutic relevance.
GPR18 is an orphan G protein-coupled receptor expressed at high levels in the testis, small intestine, and immune-related cells such as lymphocytes, thymus, and spleen.
It acts as a receptor for endogenous lipid neurotransmitters, some of which also interact with cannabinoid receptors.
Known ligands include:
- N-Arachidonoylglycine
- Abnormal cannabidiol
- O-1602
- AM-251
- Cannabidiol
- Δ9-Tetrahydrocannabinol
- N-arachidonoyl ethanolamine
- Arachidonylcyclopropylamide
Antagonists include synthetic cannabidiol-related compounds CID-85469571 and O-1918.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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