Thermo Fisher Scientific PGCF Polyclonal Antibody, Biotin
PGCF 단백질을 표적으로 하는 Thermo Fisher Scientific의 Biotin 결합 다클론 항체입니다. Western blot, IHC, ICC, ELISA 등 다양한 연구 응용에 적합하며, 높은 특이성과 안정성을 제공합니다. Rabbit IgG 기반으로 제조되어 신뢰성 있는 결과를 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GUCY2F (Guanylate cyclase 2F, retinal), also known as GUC2F or RETGC2, belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
GUCY2F may play a specific functional role in the rods and/or cones of photoreceptors and may be involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
By in situ hybridization, mRNA encoding GUCY2F is found only in the outer nuclear layer and inner segments of photoreceptor cells.
Using synthetic peptide antiserum specific for each RetGC subtype, RetGC-2 (GUCY2F) can be distinguished from RetGC-1 as a slightly smaller protein in immunoblots of bovine rod outer segments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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