Thermo Fisher Scientific CD200R Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CD200R1/CD200R/OX2R.

Target Information

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is restricted to the surfaces of myeloid lineage cells and the receptor–substrate interaction may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells.
Further mouse studies of a gene related to CD200R suggest that the receptor may control myeloid function in a tissue-specific manner.
Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.