Thermo Fisher Scientific PTPRA Polyclonal Antibody
Rabbit polyclonal antibody against human PTPRA for ICC/IF applications. Recombinant PTPRA used as immunogen. Supplied unconjugated in PBS with glycerol. High specificity and affinity-purified for reliable protein phosphorylation studies.
- 판매단위
- pk
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PTPRA. Recombinant protein control fragment (Product #RP-107694) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2662626 |
Product Specific Information
Immunogen sequence:
EPVKEEAKTSN PTSSLTSLSV APTFSPNITL GPTYLTTVNS SDSDNGTTRT ASTNSIGITI SPNGTWLPDN QFTDARTEPW EGNSSTAATT PETFPP
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 80%
Target Information
Phosphorylation of receptors by protein kinases is a process that can be reversed by protein phosphatases. Coordinated control of kinases and phosphatases allows cells to switch between phosphorylated and dephosphorylated states in response to environmental stimuli. Dysregulation of these processes can lead to uncontrolled cell growth and developmental disorders. Regulation of phosphatase activity may involve expression changes, localization, phosphorylation, and endogenous inhibitors. Because most phosphatases are not strictly substrate-specific, variations in their activity can broadly affect signaling pathways and physiological responses.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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