Thermo Fisher Scientific PTPRA Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF): 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
EPVKEEAKTSN PTSSLTSLSV APTFSPNITL GPTYLTTVNS SDSDNGTTRT ASTNSIGITI SPNGTWLPDN QFTDARTEPW EGNSSTAATT PETFPP

Highest antigen sequence identity to the following orthologs:

• Mouse: 80%
• Rat: 80%

Target Information

Phosphorylation of receptors by protein kinases is a process that can be reversed by protein phosphatases. Coordinated control of kinases and phosphatases allows cells to switch between phosphorylated and dephosphorylated states in response to environmental stimuli. Dysregulation of these processes can lead to uncontrolled cell growth and developmental disorders. Regulation of phosphatase activity may involve expression changes, localization, phosphorylation, and endogenous inhibitors. Because most phosphatases are not strictly substrate-specific, variations in their activity can broadly affect signaling pathways and physiological responses.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.