Thermo Fisher Scientific GTF3C4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GTF3C4 protein. Validated for WB and ICC/IF applications. High specificity and affinity purified by antigen chromatography. Supplied as liquid form with 0.2 mg/mL concentration, suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GTF3C4. Recombinant protein control fragment (Product #RP-105475) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665116 |
Product Specific Information
Immunogen sequence:
FWRFKLFLLRI LYQSMQKTPS EALWKPTHED SKILLVDSPG MGNADDEQQE EGTSSKQVVK QGLQERSKEG DVEEPTDDSL PT
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 81%
Target Information
Essential for RNA polymerase III to synthesize small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.
Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3.
May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through interactions with BRF1, POLR3C, and POLR3F.
May be localized close to the A box. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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