Thermo Fisher Scientific TLR11 Polyclonal Antibody
TLR11 단백질을 인식하는 토끼 폴리클로날 항체로 마우스 시료에 반응. Western blot과 ICC/IF에 사용 가능. 1 mg/mL 농도의 액상 형태로 PBS 버퍼에 0.02% sodium azide 포함. 냉장 또는 냉동 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153285 |
Product Specific Information
- Suggested positive control: RAW264.7 cell lysate
- PA5-20057 can be used with blocking peptide PEP-0176
Target Information
The Toll-like receptor (TLR) family in mammals comprises transmembrane proteins characterized by multiple leucine-rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. TLRs are conserved mediators of innate immunity essential for microbial recognition.
TLR11 specifically responds to uropathogenic bacteria rather than known TLR ligands. TLR11-deficient mice are highly susceptible to kidney infections caused by uropathogenic bacteria, suggesting a protective role in the urogenital system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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