Thermo Fisher Scientific TLR11 Polyclonal Antibody
Mouse TLR11 인식용 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 최적화됨. 1 mg/mL 농도의 액상형 제품이며 PBS 버퍼 및 sodium azide 포함. RAW264.7 cell lysate를 양성 대조로 권장하며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153480 |
Product Specific Information
- A suggested positive control is RAW264.7 cell lysate.
- PA5-20055 can be used with blocking peptide PEP-0174.
Target Information
The Toll-like receptor (TLR) family in mammals comprises transmembrane proteins characterized by multiple leucine-rich repeats in the extracellular domain and IL-1 receptor motifs in the cytoplasmic domain. The TLR family mediates innate immunity and is essential for microbial recognition. TLR11 specifically responds to uropathogenic bacteria rather than known TLR ligands. TLR11-deficient mice are highly susceptible to kidney infections by uropathogenic bacteria, indicating a protective role in the urogenital system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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