Thermo Fisher Scientific GPX1 Polyclonal Antibody
Thermo Fisher Scientific의 GPX1 Polyclonal Antibody는 Mouse 및 Rat 시료에서 반응하며 Western blot에 최적화된 Goat IgG 항체입니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS buffer와 BSA를 포함합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DYTEMNDLQKRLGPR (aa 53–67) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933575 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins that catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione.
There are several isoforms differing in primary structure and localization:
- GPx1 (cGPx): Classical cytosolic/mitochondrial, selenium-dependent enzyme and first discovered GPx family member.
- GPx2 (GI-GPx): Intracellular enzyme expressed only at the epithelium of the gastrointestinal tract.
- GPx3 (pGPx): Extracellular plasma GPx mainly expressed by the kidney and released into blood circulation.
- GPx4 (PH-GPx): Expressed in most tissues; reduces hydroperoxides integrated in membranes, hydroperoxy lipids in LDL, or thymine.
All mammalian GPx family members, except Cys-containing GPx3 and epididymis-specific secretory GPx (GPx5), possess selenocysteine at the active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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