Thermo Fisher Scientific GSTM2 Monoclonal Antibody (1E10)

Applications 및 Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
SEKEQIREDI LENQFMDSRM QLAKLCYDPD FEKLKPEYLQ ALPEMLKLYS QFLGKQPWFL GDKITFVDFI AYDVLERNQV FEPSCLDAFP NLKDFISRFE

Target Information

At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.
GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual’s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.