Thermo Fisher Scientific GSTM1 Monoclonal Antibody (3B10)

Applications

• ELISA (ELISA)
  Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MPMILGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the mu class, which functions in detoxification of electrophilic compounds such as carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products via conjugation with glutathione.
The mu class genes are clustered on chromosome 1p13.3 and are highly polymorphic, influencing susceptibility to carcinogens and drug toxicity. Null mutations of this gene are associated with increased cancer risk due to heightened sensitivity to environmental toxins. Multiple protein isoforms are encoded by transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.