Thermo Fisher Scientific TIM3 Monoclonal Antibody (G003.1)
인간 TIM3 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(파라핀) 분석에 적합합니다. 단백질 A로 정제된 액상 형태이며, -20°C에서 보관합니다. 면역 연구 및 자가면역 질환 관련 기초 연구용으로 활용됩니다.
- 카탈로그번호
- 34073-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TIM3 Monoclonal Antibody (G003.1)
Thermo Fisher Scientific TIM3 Monoclonal Antibody (G003.1)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:100–1:200
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G003.1 |
| Immunogen | Recombinant human TIM-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | Tris, pH 7.3–7.7, with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-domain containing-3) is a 281 amino acid, Type-1 Th1-specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells.
TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved tyrosine phosphorylation motif in the cytoplasmic region.
It is involved in macrophage activation and induction of autoimmune diseases, down-regulates Th1-mediated immune responses, and facilitates immune tolerance.
Pathological significance includes association with experimental autoimmune encephalomyelitis (EAE), a Th1-dependent autoimmune disease, enhancing its severity in mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.