Thermo Fisher Scientific DCLK1 Polyclonal Antibody
DCLK1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 항원 친화 크로마토그래피로 정제. 장기 보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific DCLK1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:10,000
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DCLK1 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.77 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735709 |
Product Specific Information
- Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse hippocampus, mouse brain, rat brain
- Predicted Reactivity: Chicken (91%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DCAMKL1 (DCLK1), also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate polymerization, a C-terminal serine/threonine kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase, and an intermediate serine/proline-rich domain mediating protein-protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and microtubule polymerization independent of its kinase activity. It is involved in neuronal migration, retrograde transport, apoptosis, and neurogenesis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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