Thermo Fisher Scientific PDE11A Polyclonal Antibody
PDE11A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, IP 등 다양한 실험에 적용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로 안정적이며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunoprecipitation (IP) | 1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–150 on PDE11A protein, common to all PDE11A variants |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris glycine, pH 7.4–7.9, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2162603 |
Product Specific Information
Recommended positive controls: Rat testis, skeletal muscle, kidney, and brain.
Target Information
The 3’,5’-cyclic nucleotides cAMP and cGMP act as second messengers in diverse signal transduction pathways. 3’,5’-cyclic nucleotide phosphodiesterases (PDEs) hydrolyze cAMP and cGMP to 5’-monophosphates, downregulating their signaling. PDE11A belongs to the PDE superfamily. Mutations in PDE11A are associated with Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA1-31146_PDE11A_Q9HCR9-1_Rabbit.svg, PA1-31146_PDE11A_Q9HCR9-1_Rabbit_PDP.jpeg)
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