Thermo Fisher Scientific PDE11A Polyclonal Antibody
PDE11A 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간·마우스·랫트 반응성을 보입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunoprecipitation (IP) | 1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to C-terminal amino acids 454–468 of Human PDE11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris glycine, pH 7.4–7.9, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% thimerosal, 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2236936 |
Product Specific Information
Recommended positive controls: Rat testis, skeletal muscle, kidney, and brain.
Target Information
The 3’,5’-cyclic nucleotides cAMP and cGMP function as second messengers in various signal transduction pathways. 3’,5’-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to their corresponding 5’-monophosphates, providing a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene can cause Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been identified for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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