Thermo Fisher Scientific METTL3 Polyclonal Antibody
METTL3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트에 반응. 핵 스펙클에서 발현되는 METTL3 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | – |
| ELISA | 1 µg/mL | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–156 of human METTL3 (NP_062826.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.67 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914762 |
Product Specific Information
- Positive test controls: 293T, HT-1080, NIH/3T3, Mouse testis, Mouse brain, Rat spleen
- Subcellular localization: Nucleus speckle
Immunogen sequence:
MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSGG PKPSTASAVP ELATDPELEK KLLHHLSDLA LTLPTDAVSI CLAISTPDAP ATQDGVESLL QKFAAQELIE VKRGLLQDDA HPTLVTYADH SKLSAM
Target Information
METTL3 is the 70 kDa subunit of MT-A, part of N6-adenosine-methyltransferase.
This enzyme mediates posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine (m6A).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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