Thermo Fisher Scientific HIV1 gp120 Recombinant Rabbit Monoclonal Antibody (11)
HIV-1 gp120 단백질에 특이적인 재조합 토끼 단클론 항체로 높은 특이성과 민감도 제공. WB 및 ELISA에 사용 가능하며, 보존제가 없는 액상 형태. HEK293 세포에서 발현되고 Protein A로 정제됨. 연구용으로 HIV-1 감염 기전 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 11 |
| Immunogen | Recombinant HIV-1 gp120 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785766 |
Additional Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin–free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody specifically recognizes HIV-1 gp120 (Glycoprotein 120).
Target Information
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is mediated by envelope (Env) glycoproteins, present as trimers of gp120/gp41 complexes.
The gp120 subunit interacts sequentially with the CD4 receptor and co-receptors CCR5 or CXCR4, inducing conformational changes that enable gp41 to mediate fusion between viral and host cell membranes.
Cleavage of Env into gp120 and gp41 components is essential for activation of fusogenic activity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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